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CB-1 Weight Gainer

8 Customer Reviews

Supragenix claims that CB-1 Weight Gainer is a supplement that allegedly offers a weight gain solution for those with fast metabolisms or weak appetites.

CB-1 Weight Gainer Review – How Effective Is This Supplement?

Updated on: Mar 13, 2020

What is CB-1 Weight Gainer?

Supragenix claims that CB-1 Weight Gainer is a natural weight gain pill with allegedly clinically proven results.

As the many unwanted conditions associated with obesity remain at the forefront of most health and wellness discussions, Supregenix states that those that struggle to gain weight are often overlooked.

Being underweight has its inherent risks as well. Such issues include malnutrition, heart issues, and kidney dysfunction, which commonly related to being underweight.

Supragenix claims that taking 1 capsule 30-60 minutes before each meal can deliver lasting weight gain results. But is it that simple?

While Supregenix claims to offer a weight gain solution that is backed by science, they’re also quick to share this disclaimer:

*Results featured may not be typical. Weight gain results depend on a variety of factors and are not guaranteed. Individual results vary.

This conflicting information can be challenging to weed through.

In this article, we’ll review the active ingredients and highlight any available scientific support for their safety and efficacy.

CB-1 Weight Gainer Ingredients and Their Efficacy

Supregenix prides itself on offering a product free of steroids and other potentially harmful substances. They claim that their blend of herbs, vitamins, and minerals are safe and effective.

In this section, we’ll take a closer look at the ingredients to determine if there is any available scientific support for their ability to offer the weight gain you need.

The Ingredients

Each capsule of CB-1 Weight Gainer contains the following:

  • Vitamin D3 – 1,500 IU (375% of your Daily Value)
  • Zinc – 6mg (40% of your Daily Value)
  • Maximum Strength Weight Gain Blend – 405mg
    • Echinacea Purpurea Powder
    • Dodeca-2E, 4E, 8Z, 10E/Z-tetraenoic isobutylamides
    • Dodeca-2E, 4Z-diene-8, 10-diynoic isobutylamide
    • Undeca-2Z, 4E-diene-8, 10-diynoic isobutylamide
    • Echinacea Angustifolia Powder
    • Dodeca-2E, 4E, 8Z, 10E/Z-tetraenoic isobutylamide
    • Undeca-2-ene-8, 10-diynoic isobutylamide
    • Dodeca-2E, 4E-dienoic isobutylamide
    • Soy Lecithin
    • Vitamin E (mixed tocopherols)

These ingredients are broken up into 3 main categories: Vitamins, Minerals and Isobutylamides.


CB-1 Weight Gainer includes both vitamins D and E, though E is part of their weight gain blend – we’ll discuss that a bit later.

Vitamin D helps to maintain strong bones and teeth, while also potentially reducing your risk for some chronic diseases.

As deficiency is common, supplementation is often necessary. With three servings of CB-1 Weight Gainer, you’ll receive more than 10x the recommended daily value. This dose should help prevent or improve deficiency.

With respect to weight gain, our literature review did not produce any evidence that Vitamin D offers a benefit. In fact, it may have the opposite effect.

In a recent study, 50,000 IU per week over 6 weeks significantly reduced body weight, BMI, waist circumference, and hip circumference.

Though Vitamin D is necessary for overall health, it may offer weight loss benefits rather than aiding weight gain.


Zinc is an essential mineral that is often deficient in older adults and those that opt for plant-based diets. Low levels can be associated with many unwanted effects so ensuring your diet or supplement meets your needs is important

CB-1 Weight Gainer includes 40% of the recommended daily value of zinc in each pill. Consuming 3 pills each day means you’ll exceed your recommended daily value, so this supplement may help improve or prevent deficiency.

Zinc is involved in many vital reactions in your body and may offer many benefits such as reducing inflammation, promoting wound healing, and boosting immune function.

Our literature review did not produce any support for zinc’s ability to assist in weight gain. Zinc seems to offer favorable results in managing blood sugar and reducing weight.

In a randomized trial, 30mg of zinc daily for 4-weeks significantly decreased both BMI and body weight in obese subjects.

While including this mineral can serve to bolster your nutrition, zinc does not appear to provide weight gain benefits.

Maximum Strength Weight Gain Blend

As in most proprietary blends, the company provides only the total combined amount of all ingredients. As they do not offer details regarding the amount of each specific ingredient, we can’t compare them to doses included in scientific research.

Nonetheless, the proposed weight gain benefits of this supplement may be primarily related to echinacea, isobutylamide, soy lecithin, and Vitamin E.

Echinacea is obtained from flowering plants found in the US, Canada, and Europe. For centuries, it has been thought to offer a number of health benefits like wound healing and boosting immune function.

Cannabinoid (CB1) receptors found in your brain can induce hunger when stimulated. In a laboratory study, echinacea purpurea root extract demonstrated an ability to stimulate these receptors, though this action has yet to be demonstrated in human subjects.

Isobutylamides are compounds found in echinacea and thought to be the active ingredient responsible for its proposed benefits. Multiple isobutylamides are likely included in this blend to further stimulate hunger, but again, support for this action is lacking.

Lecithin are fatty substances found in both animals and plants that are used as an additive to thicken foods. Soy is a common source for this substance.

While soy lecithin may offer memory and mood-boosting effects, its role in weight gain has not been demonstrated.

In addition to offering antioxidant effects, Vitamin E may boost immune function and promote blood flow.

While its antioxidant benefits have been well studied, there is no information describing a potential role in weight gain.

While CB-1 Weight Gainer offers some ingredients that may be valuable, weight gain does not seem to be one of the benefits. Ingredients like Vitamin D and zinc seem to be associated with weight loss.

While some laboratory studies point to a possibility for echinacea to boost hunger, this support is not available in human studies.

Supragenix claims that a randomized trial backs their product; our literature review did not produce this information. If available, this would represent the only study examining the weight gain effects of these ingredients in humans.

We reached out to the company to see if they’d share the study details, but we did not hear back.

CB-1 Weight Gainer Side Effects and Safety

Vitamin D is safe at much larger doses than what is included in CB-1 Weight Gainer. Vitamin D is fat-soluble, so the excess is harder to get rid of when compared to the water-soluble vitamins that are easily excreted in urine.

Adverse effects are unlikely at daily intakes below 10,000 IU/day; digestive symptoms may be an early sign of consuming too much.

Consuming excess zinc may lead to nausea, vomiting, stomach pain, and fatigue. These effects are more likely at doses much higher than what is offered in CB-1 Weight Gainer.

As Supragenix does not offer information for the individual ingredients in their Weight Gain Blend and available scientific support is lacking, we don’t have much to compare. Also, recommended daily allowances are not provided for ingredients such as extracts.

Since a safety profile can’t be described for this supplement, it is best to include your physician in the decision on whether or not you should try the product or similar ones.

How Much Does It Cost?

The CB-1 Maximum Strength Weight Gainer can be purchased directly from the Supragenix site. Their products do not seem to be available from other retailers as of yet.

If you’re consuming 3 meals per day, a single 90 capsule bottle will last you one month. One time orders run $69.98 per bottle.

You have a choice between standard processing (free) or rush processing ($6.99) in which your order ships in 1-day or less.

You’ll save $20 per bottle if you join the CB-1 Success Program. Joining the program locks you in at $49.98 per month where you will receive a bottle each month until you cancel.

Lastly, Supragenix backs your purchase with their 30-day guarantee. If you’re unsatisfied, call (888) 528-5551to process your refund.

Available Alternatives

There are many weight gain supplements currently available on the market, though none seem to offer a blend similar to CB-1 Weight Gainer.

The vitamins and minerals, as well as the echinacea included in this supplement are available individually from a variety of retailers. Isobutylamides seem to be a little harder to come by, however.

Due to the lack of available research for CB-1 Weight Gainer’s efficacy in weight gain, why would you want to go through the trouble of finding these ingredients individually even if you did save money?

There are other products available that may offer weight gain through a different mechanism.

High-calories supplements like Serious Mass from Optimum Nutrition can assist in weight gain by boosting your calorie totals with daily use. You can pick up a tub at GNC for $39.99, though this offers only 8 total servings.

This particular product contains a whopping 1250 calories in every 2 scoops.

Watch out for products like these, however. This powder also contains over 20g of sugar per serving and a total of 253 carbs.

Remember that if you mix with a liquid other than water, you’ll only add to these totals.

These products often contain sugar and preservatives, so be sure to check the label.

The Bottom Line

The proposed weight loss benefits of CB-1 Weight Gainer do not seem to be backed by research. In fact, this supplement contains a couple of ingredients that have been demonstrated to assist with weight loss.

As the available research is lacking and Supragenix does not offer information for the individual proprietary blend ingredients, we can’t determine how safe this supplement is. This product also comes with a pretty hefty price tag.

In light of these factors, it’s probably best to seek weight gain assistance elsewhere.

Supragenix also mentions that increasing your caloric intake is necessary with the use of their product, though increasing the calories you consume alone can result in weight gain.

For example, if you eat an additional 500 calories daily, you’ll gain 1lb over 7-days.

If you feel you are underweight, consult a physician. Examining your diet will likely be one of the first steps in your management.

Under the guidance of a trained professional, strategically managing your diet can be an effective way of gaining weight, while also ruling out any possible underlying medical conditions.

Supragenix claims that CB-1 Weight Gainer is a supplement that allegedly offers a weight gain solution for those with fast metabolisms or weak appetites.

Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression


  • 1 Department of Physiological Chemistry, Johannes Gutenberg-University Mainz, Duesbergweg 6, 55099 Mainz, Germany.
  • PMID: 19285266
  • DOI: 10.1016/j.beem.2008.09.003

Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression

Both agonists (e.g. Delta(9)-tetrahydrocannabinol, nabilone) and antagonists (e.g. rimonabant, taranabant) of the cannabinoid type-1 (CB(1)) receptor have been explored as therapeutic agents in diverse fields of medicine such as pain management and obesity with associated metabolic dysregulation, re … ]]>